Starting from the encounter of the first case of H1N1 influenza virus in the year 2009 reported from the town of Mexico to its lay out across the globe; H1N1 virus has affected thousands of people in India. Since then this seasonal virus keeps on mutating (S181T and I312V) becoming more and more harmful and dangerous causing various serious complications. With its ability to regenerate and mutate at a faster rate this virus has RNA as its genetic material which is a combination of three different species; humans, avian and swine, targeting a larger spectrum of hosts turning out to be extra severe. Evidence have shown that the elderly and children are the most affected by the virus due to low immune response by the body. Common symptoms of H1N1 include fever, chills, sore throat ,etc. The situation may turn fatal if left untreated.