Introduction: Vitamin D 3 deficiency continues to be an unrecognized epidemic in many populations around the world. Vitamin D is important for the absorption of calcium, and bone formation and maintenance Materials and Methods: 150 patients enrolled for the study along with control, serum analyzed by vitros – Eci- dry chemistry analyzer, (Johnson–Johnson). Study done in CRGH Hospital, in R.D. Gardi Medical College, Ujjain, Madhya Pradesh, during Dec. 2015- Sep. 2016. All data were analyzed by Graph pad. Prism 8. Results: We have found decrease level of Vitamin D in patients with higher serum PSA level, p value < 0.0001. Conclusion: Supplementation of Vitamin D is required for developing countries especially for older having higher risk of prostate carcinoma.

Keywords: Vitamin D; Prostate carcinoma; Calcium; Phosphorous.