Objectves: To compare the effectiveness of aerobic exercises and resisted exercises in modifying lipid profile in sedentary and overweight individuals. Background: Sedentary and overweight are known risk factors for coronary heart disease. Exercise (aerobic or resisted) modifies the lipid profile. There exist a need for comparison which is efficient in modifying lipid profile. Methodology: It is a pre and post comparative experimental study dividing Group A as aerobic and Group B as resisted training. 30 subjects aged between 21-40 years with borderline lipid levels were recruited as 15 in each group. The subjects were given Baecke physical activity questionnaire and BMI was calculated. Then pre and post test values of LDL, TG and HDL were taken in both groups. Group A was given with aerobic exercise training of jogging for period of four weeks whereas Group B was given with resistance training for four weeks(50% of 1-RM, 75 % of 1-RM, 100% of 1-RM) 10 repetitions of squats, leg curls, leg press, knee extension exercises in 3 workouts per session. Results: The results showed that there is a significant difference between pre and post values of LDL, TG and HDL in both the groups with significance level of p<0.05. When compared between the groups it is observed that the resisted exercises are more effective than aerobic exercises. Conclusion: Resistance training was found to be effective when compared with aerobic training in modifying lipid profile in sedentary and overweight individuals.