Context: Pancytopenia  is  not  a disease  but a clinichematological entity encountered in day to day practice. Bone marrow examination with peripheral blood finding and relevant biochemical test with  radiological  finding play important role in diagnosing and understanding the causes  of pancytopenia which further determine  the management and prognosis. Aim: To obtain  detailed  clinical and  hematological spectrum of  the common disorders  producing pancytopenia in patient attending our tertiary care center and its causes and diagnostic approaches. Material and Method:The  study was conducted in the department of pathology Katihar Medical College, Katihar. A retrospective study including 150 cases of pancytopenia in the duration of 2018 October to 2020 October. Results: The age of the patients ranged from 2 to 80, 75% of patients out of 150 cases were of megaloblastic anemia followed by aplastic  anemia (10%), kalazar (8%),  acute leukemia (6%), malaria (4%), myelodysplastic syndrome (1%) and tuberculosis (1%). Conclusion:The  study  concluded  that bone  marrow examination  along  with  peripheral blood finding  and radiological finding with biochemical  finding  helps  to diagnose and understand the causes and management of pancytopenia.

Keywords: Pancytopenia Anaemia; Kalazar; Tuberculosis