Economic evaluation refers to the process of systemic identification, measurements, and valuation of the inputs and outcomes of two alternative activities and the subsequent comparative analysis of these. Different economic evaluation methods include Cost-benefit analysis (CBA), Cost-effectiveness analysis, Cost-minimization analysis, and Cost-utility analysis. In developing countries with limited resources, every health program cannot be implemented equally well. We have to choose one over another. It not only saves resources but also saves time as well. For doing so, we must analyze its effectiveness justifying its cost. Monetization of health outcomes is not an appropriate tool to evaluate the effectiveness of a health program. For doing so, we use Cost-effectiveness analysis as a method of economic analysis in order to compare the relative cost and effectiveness of two or more health programs. CEA methods are developed and refined by CHOICE (Choosing Intervention that is Cost Effective). Thus it helps the economists in decision making, i.e., making choices between alternatives. However, vaccines in animals are developed using the Cost-Benefit ratio.