The objectives of the study were to assess the knowledge of Patients regarding Diabetes Mellitus and to assess the home management of Diabetes Mellitus. Method: Quantitative Research with descriptive comparative research design was used. Structured questionnaire was used to assess the knowledge and home management of Diabetes Mellitus. Convenience sampling was adopted to select 100 Diabetic Patients from a selected urban community in New Delhi. Results: Data was analyzed using Descriptive and Inferential statistics. The findings showed that 52% of the samples had adequate knowledge on Diabetes Mellitus and 56% of the samples had unhealthy home management score of Diabetes Mellitus. Conclusion: The present study revealed that most of the samples had unhealthy home management score of Diabetes Mellitus. The study thus implies that people in the community should be taught and demonstrated the healthy home management of Diabetes Mellitus.