Introduction: Alcoholism is a foremost public health problem afflicting people all over the world resulting in misery and untold sufferings to the family of the alcoholic very especially to the spouse. Alcohol use disorder seem to be an incapacitate sickness which manifests itself as a disorder of conduct. Spouses feel difficult to manage married life and feel stress. This study delineates how wives in Sikkim cope with their alcoholic husbands, and what motivates them to carry on in spite of the surrender of the husbands to the addiction. Methods: This study is a descriptive co-relational, conducted in in patient department of District Hospitals of Sikkim among 60 spouses of alcohol use disorder were AUDIT scale was used to assess the pattern of alcohol used by husband and the spouses were selected through purposive sampling technique. The data was collected through standardized DASS scale to assess the stress, depression anxiety experienced by the spouses of alcohol use disorder and structured coping scale was to used to find out the positive and negative coping strategies adopted by them for which the validity and reliability was established by the panel of experts. Data analysis was done using SPSS version 15 applying descriptive and inferential statistical methods. Results: The Findings of the study revealed that among 60 spouses, 41.67% had experience severe stress, 33% moderate depression and 38.33% had moderate anxiety. The findings also revealed that majority of the spouses reported significantly more familial and social focused negative coping strategies, such as distancing, self-controlling and anger displacement when they are frightened and when they do not wish to confront the situation in order to avoid conflict with the stressful situation. It was also seen that stress and depression is depend upon the factors like type of marriage, type of family, habit of alcoholism before marriage among husband, and family history of alcoholism among spouses of alcohol use disorder (p < 0.05). Discussion and conclusion: The study concludes that spouses of alcohol use disorder are severely stressed which hampered their marital life, caring of children, negative attitude towards husband, loss of respect and dignity.