A study was carried out to assess the effectiveness of planned teaching programme on knowledge regarding osteoporosis among the women residing in selected rural areas. This study was based on the quantitative approach. The samples were 60 women (30 in experimental group and 30 in control group) residing in selected rural areas during the study period. Non probability purposive sampling technique was used. In this study, the comparison of the knowledge scores of the experimental and control group reveals that the mean difference knowledge score of the experimental group was 10 and the mean difference knowledge score of the control group was 0.8. The calculated ‘t’ value is 23.08, which is greater than the tabulated ‘t’ value 2 at 5% level of significance. Thus it was statistically interpreted that the planned teaching programme regarding osteoporosis was effective in the women in the experimental group, and the level of knowledge is significantly increased in the experimental group than in the control group.