The waste generated from medical activities can be hazardous, toxic and even lethal because of their high potential for disease transmission and injury that also result in environmental degradation. An adequate and appropriate knowledge of Bio Medical Waste Management among the students of MBBS & Nursing is the first step to safe disposal hazardous hospital waste. Appropriate management of health care waste is then a crucial component of environmental health protection, and it should become an integral feature of health care services.A Quantitative Non­Experimental Research using Descriptive Research Design was used. Data was collected from 100 BSc(Hons) Nursing 1st year students and  MBBS 2nd year students of Jamia Hamdard, New Delhi, in the month of April 2016. Structured Knowledge Questionnaire was used to assess knowledge regarding Bio Medical Waste Management. The study findings revealed that the mean knowledge score (17.74) of MBBS 2nd year students was higher than that of the mean knowledge score (13) of BSc. (Hons.) 1st year students. Out of 50 BSc. (Hons) Nursing 1st year Students, 6 students had below average scores, 32 students had average scores and 12 students had above average scores, whereas out of 50 MBBS 2nd year students, none had below average scores, 33 students had average scores and 17 students had above average scores.