Epidemics have been inevitable part of human race since ages. Beta coronavirus family is known to have caused 3 highly infectious diseases namely SARS, MERS and COVID-19, spreading over maximum part of world. This review paper aims to compare all the 3 pandemic under sub-headings i) origin ii) viral pathogenicity iii) receptors used by the virus to infect the cells iv) symptoms v) public health measures taken. Research papers published in Google scholar and PubMed were used to gather information. It was summarized that SARS-CoV, MERS-CoV, SARS-CoV-2 have zoonotic sources and MERS spreading through dromedary camels. The case fatalities of MERS are noticed to be highest due to its high virulence. The infection rate of SARS-CoV-2 is highest all three. Both SARS-CoV and SARS-CoV-2 use the same antigen receptor called ACE-2 and MERS-CoV using DPP-4 as receptor protein. All the 3 are respiratory syndromes but may have other clinical symptoms owing to the presence of receptors. Strict public health interventions have to be helpful to control SARS and MERS. Various countries have reacted differently to the COVID-19 emergency and it has shaped the way virus affects the country. The gathered data can be useful in further research and also help in assessment of the diseases better.