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Journal of Forensic Chemistry and Toxicology

Volume  9, Issue 1, January – June 2023, Pages 53-57
 

Case Report

Reperfusion Induced Fatal Hemorrhagic Myocardial Infarction: A Case Report

Gokul G 1, Abdul Raoof MP 2, Abhishek Yadav 3, Amar Ranjan 4, Manivel. S 5

1,5 Junior Resident, 2 Senior Resident, 3 Additional Professor, 4 Additional Professor, Institute Rotary Cancer Hospital, Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, New Delhi 110029, India.

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DOI: http://dx.doi.org/10.21088/jfct.2454.9363.9123.4

Abstract

Sudden death due to coronary artery disease is the leading cause of death globally. Occlusive coronary artery disease results in ischemia of myocardial tissue and subsequent infarction. Various treatment modalities like blood thinners, percutaneous coronary intervention (PCI) etc are being employed in the treatment of acute myocardial infarction (MI). However, these modalities have their own limitations. In this case, reperfusion therapy resulted in hemorrhagic myocardial infarction (HMI) with a fatal outcome. An adult male with history of sudden collapse was brought to the emergency department, where he was declared as brought dead. He underwent reperfusion therapy and was on blood thinners, 4 days before the incident. On autopsy, we could find the features of hemorrhagic myocardial infarction grossly and the same was confirmed histopathologically. Though reperfusion injuries are commonly documented, deaths due to hemorrhagic myocardial Infarction, which is one of the rare complications of reperfusion therapy, are rarely reported. The important role of forensic pathologists in this case is to identify the rare causes, which led the patient to death during management of occlusive coronary artery disease.


Keywords : Occlusive coronary artery disease; Reperfusion therapy; Hemorrhagic Myocardial infarction; sudden death.
Corresponding Author : Abhishek Yadav, Additional Professor, Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, New Delhi 110029, India.