Aim: To assess the knowledge of primiparous and multiparous mothers regarding weaning practices in infants and to improve their knowledge. Objective: Objectives of the study to assess the knowledge of primiparous and multiparous mother regarding weaning practices in infants and tofind out the association between demographic variables with knowledge scores of primiparous and multiparous women regarding weaning practices in infants.

Methods: The research method adopted for this study is a quantitative approach. The research design adopted for this study was a comparative design. Formal Permission was obtained from the concerned authorities nonprobability purposive sampling technique was used to select the sample for the study. The sample consists of 60 primiparous mothers and 60 multiparous mothers, The instrument used for the data collection is a self-structured knowledge questionnaire. Collected data were analyzed by using descriptive and inferential statistics.

Results: After tabulation and analysis 60 samples were taken from primparous mothers in that majority of the subjects 41.6% (25) were in the age group of 19-23 years. Majority of the study samples were Hindus 32 (53.3%). Almost 34.4%(20) had education status SSLC to PUC. Most of the mothers 58.4%(35) got information from family members and friends. Most of the mothers 20 (34.4%) are having an income of 15001 and above. 60 samples were taken from multiparous mothers in the majority of the subjects 36.6% were in the age group of 29-33 years. The majority of the study samples were Hindus 30 (50%). Almost 34.4%(20) had education status SSLC to PUC. Most of the mothers 40%(24) were got information from family members and friends. Most of mothers 23(348.4%) are having income of 5001-10000. 3(5%) primiparous samples and 17(28.4%) multiparous samples had adequate knowledge regarding weaning practices. 20(33.4%) and 35(58.3%) respectively from primi and multiparous mothers had moderate knowledge and assessed that 37 (61.6%) samples from primiparous mothers and 8(13.3%) samples from multiparous mothers had inadequate knowledge regarding weaning practices in infants.

Conclusion: The study findings showed that the multiparous mothers are having more knowledge than primiparous mothers regarding weaning practices in infants and there are some demographic variables associated with knowledge regarding weaning practices in infants.