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RFP Journal of Biochemistry and Biophysics

Volume  3, Issue 1, Jan-June 2018, Pages 12-14
 

Original Article

Comparison of Lipid Profile Levels in AMI Patients With and Without Diabetes Mellitus

Savita Deshmukh1, Raviraj Naik2, Ranjana Deshmukh3

1,2Assistant Professor, Dept. of Biochemistry; Indian Institute of Medical Science & Research, Jalna, Maharashtra 431202, India. 3Consulting Physician; Dr. Hedgewar Hospital, Aurangabad, Maharashtra 431005, India.

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Abstract

Present study was aimed to assess lipid profile in diabetic and non-diabetic patients with history of myocardial infarction.

Methods: Study conducted in the Department of Biochemistry, Indian Institute of Medical Science and Research, Warudi, Tq. Badnapur, District Jalna (M.S.)in collaboration with Hedgewar hospital during period of 2015-17. Biochemical investigations include fasting blood sugar, postprandial blood sugar and lipid profile (total cholesterol, triglyceride, LDL-cholesterol, HDL-cholesterol and VLDL).

Results: Present study shows significant increase in the levels of triglyceride, LDL-cholesterol, while cholesterol level increases non-significantly. HDL-cholesterol levels decreased significantly in patients of myocardial infarction (MI) with diabetes mellitus compared to non-diabetic patients with history of myocardial infarction.

Conclusion: Diabetic patients with history of myocardial infarctionwere having significantly deranged lipid parameters and higher risk of dyslipidemic complications as compared to nondiabetic patients with history of myocardial infarction. 

Keywords: AMI (Acute Mycocardial Infarction); HDL (High Density Lipoprotein; LDL (Low Density Lipoprotein); Diabetic & Non-Diabetic.


Corresponding Author : Raviraj Rajan Naik, Assistant Professor, Dept. of Biochemistry; Indian Institute of Medical Science & Research, Jalna, Maharashtra 431202, India.