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RFP Journal of Biochemistry and Biophysics

Volume  5, Issue 1,  January – June 2020, Pages 15-18
 

Review Article

Evaluation of Diagnostic Significance of Novel Corona Virus

S S Haque

Biochemist, Department of Biochemistry, Indira Gandhi Institute of Medical Sciences, Patna, Bihar 800014, India.

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Abstract

In the current scenario viral diseases continue to emerge a serious public health hazards. Viruses are parasite like molecules that cannot reproduce by itself, for the production of number of viruses it requires cell machinery. Coronaviruses (CoVs) (order Nidovirales, family Coronaviridae, and subfamily Coronavirinae) are a positive sense, single-stranded RNA genome of 26 to 32 kilobases (kb) in length, and enveloped viruses. It genomes is largest in RNA viruses. Many diagnostic tests for coronavirus disease 2019 (COVID-19) are available so far. An RTPCR test is considered very reliable because it detects less number of virus particles in swabs. D-dimer one of the markers of inflammation, its levels were higher in COVID-19 patients. In this review we discuss about the various diagnostic test for corona virus and their reliability


Keywords: Coronaviruses; Diagnosis; RT-PCR; D-Dimer; Prognosis
 


Corresponding Author : S S Haque.