Background: Pulmonary thromboembolism (PTE) is a major health problem with significant mortality and morbidity. Although rapid advances have taken place in the diagnosis and management of VTE, PE is still an underreported entity from India. We are intended to study various clinical presentations with suspected pulmonary embolism and evaluate the abnormalities in investigations. Method: The present study is prospective and observational study, being carried out on suspected cases of pulmonary embolism. All patients admitted during the study period taken as a sample who fulfills inclusion and exclusion criteria. Result: Male preponderance (66% cases are male as compared to 34% females) with increased prevalence of pulmonary embolism after the age of forty years. Dyspnea (92%) is the most common presenting symptom followed by chest pain and cough (44% of patients). Hemoptysis was present in 16% of the patients. Most common ECG abnormality in our patients was sinus tachycardia (88%). On CT pulmonary angiography thrombi were found in lobar and segmental branches of pulmonary artery in 90%. Conclusion: Early recognition and aggressive and appropriate therapy improves outcome in this potentially fatal condition. Prevention of VTE in high-risk cases by lifestyle modification and early ambulation in hospitalized cases especially in Indian setting should be universally practiced. More emphasis need to be given on the high index of suspicion, early and appropriate diagnostic tests, prompt therapy, and preventive measures to improve the outcome in VTE patients.