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DOI: http://dx.doi.org/10.21088/ijem.2395.311X.4318.10

Abstract

Background: AIDS is caused by HIV, a non-transforming human retrovirus belonging to the lentivirus family; two genetically different but related forms of HIV, called HIV-1 and HIV-2 have been isolated from patients with AIDS.

Objective: The main objective of the current study is to investigate that the prevalence of subclinical hypothyroidism in HIV positive patients with treatment and without treatment.

Method: Those HIV positive patients which were admitted in Medicine ward or attending Medicine / ART OPD of NSCB Medical College, Jabalpur were selected for the study. The patient presented with signs & symptoms of hypothyroidism (like tiredness/weakness, dry skin, feeling cold, hair loss, constipation, dyspnoea, impaired hearing, hoarse voice, weight gain with poor appetite, difficulty Concentrating & poor memory etc.) were excluded from the study. Further, patients with diagnosed case of Thyroid disease, renal disease, Malignancy & patient receiving drugs Affecting Thyroid function were screened & were also excluded from the study.

Result: Finding of the present study shows that Thyroid Dysfunction in 200 HIV positive patients. Among those 26 patients (13%) had Thyroid Dysfunction. Out of these 26 patients, 15 were male &11were female. Thyroid Dysfunction was slightly more common in female patient (14.67%) Than male patients (12%).

Conclusion: In this present study, out of 200 HIV positive cases, 125 (62.5%) were male & 75 (37.5%) were female, age ranging from 14 to 70 years. Maximum HIV positive patients were in the age group of 26-45 years. Out of 200 HIV positive patients, 26 patients (13%) had Thyroid Dysfunction. Among these 26 patients, 23 patients (11.5%) had subclinical hypothyroidism. 88.5% cases of thyroid dysfunction were of subclinical Hypothyroidism. Prevalence of subclinical hypothyroidism was found to be slightly more among females (12%) than males (11.2%)

Keywords : Hypothyroidism; HIV; Prevalence.

Corresponding Author : Savita Aharwal, Assistant Professor, Department of Medicinee, Late Shri Lakhi Ram Agrawal Memorial Government Medical Colleg, Bendrchuwa, Raigarh, Chhattisgarh 496001, India.