Aortic dissection is a life threatening condition of the aorta. Early diagnosis and management can reduce the patient’s morbidity and mortality; hence one should have a high index of suspicion for this condition. This case reports a 53 yrs old male presenting with headache, slurring of speech, Rt leg weakness with dyspnoea and sweating. A patient of aortic dissection can present in many ways depending on the site involved and may mimic other disorders like ACS, PE or CVA. Therefore, clinicians must always be aware of aortic dissection and its different clinical manifestations.

Keywords: Aortic dissection; Pulmonary Embolism.