Introduction: In 1916, Hans Reiter described the classic triad of arthritis, nongonococcal urethritis, and conjunctivitis (Reiters syndrome) in a Prussian soldier with diarrhea, during the first world war. Reiter’s syndrome is defined as a complication of non gonococcal urethritis in which there is arthritis (mainly knees, ankles and feet), conjunctivitis, rashes, cardiac and neurological problems. Other features include; iritis, keratoderma blenorrhagicum, circinate balanitis, plantar fasciitis, Achilles tendonitis, aortic incompetence. RS is triggered by bacterial infection that enters via mucosal surfaces usually, (but not always) associated with human leukocyte antigen (HLA)- B27. Nongonococcal venereal disease (most often Chlamydia) and infectious diarrhea usually precede reiter’s syndrome. These include infections with: Shigella flexneri, Shigella dysenteriae, Salmonella typhimurium, Salmonella enteritidis, Streptococcus viridans, Mycoplasma pneumonia, Cyclospora, Chlamydia trachomatis, Yersinia enterocolitica, and Yersinia pseudotuberculosis. Campylobacter jejuni . Others include Chlamydia pneumoniæ and Ureaplasma urealiticum. 

Keywords: Urethritis; Tendonitis; Conjunctivitis; Morning Stiffness.