AbstractIntroduction: Blood Stream Infections increase the mortality rate, prolonging hospital stay in ICU, posing a challenge to the skill of not only the clinician but also to the microbiologist. Easy availability and indiscriminate use of antibiotics is leading to antimicrobial resistance.
Objective: To review the spectrum of organisms isolated and their antibiotic sensitivity pattern in the Intensive Care Unit to minimize the risk of morbidity and mortality.
Method: 235 suspected cases of septicemia from ICU were taken; co morbid illness and outcome were noted. Blood culture and their antibiotic susceptibility profile were done.
Results: Of the 235 suspected cases, 47 (20%) were culture positive with Gram Negative Organisms predominant (70.21%) over Gram Positive Organism (27.65%). Klebsiella species was the most common organism isolated (38.29%). Of the 13 GPC, 38.46% cases showed Vancomycin resistance.
Conclusion: Gram Negative Organisms were most common etiological agents with Klebsiella being most predominant. The rate of Vancomycin resistance from isolated organisms was high. Mortality rate was high (17.02%).
Keywords: Septicemia; Intensive Care Unit; Mortality; Vancomycin; Klebsiella.