Introduction: All over the world, with the increasing risk factors like obesity and sedentary lifestyle, it is expected that incidence of Metabolic syndrome (MetS) will be increasing dramatically. It is well established that the five components of MetS also individually increase the risk of cardiovascular disease.

Aims and Objectives: The aim of our study was to determine the incidence of MetS in the cases of acute myocardial ischemia; and to study the detrimental impact of syndrome and its components over the in-hospital outcome in these patients.

Methods: A total of one hundred and fifty patients of acute myocardial infarction (AMI) were included in this study.

Results: Among these 150 AMI patients (113 males, 37 females) one hundred and two (68%) met with ATP III criteria of MetS. The mean age for the entire cohort was 54.99±13.18 years. In our study high prevalence of MetS (68%) was observed in the patients of AMI and at least one risk factor of Mets was present in 98.67% of patients. Most common combination of MetS observed was a four combination of obesity+ hyperglycemia+elevated triglycerides+ low-HDl (OB+DM+HTG+low-HDL) in 16.67%. most common three components combination observed was OB+DM+HDL (8.82%). HT, DM and HDL showed significant correlation with adverse in-hospital outcome among AMI patients (p<0.05).

Conclusion: The present study concludes that there is noticeable high occurrence of metabolic syndrome and its components in the cases of AMI. In our findings hypertension showed strong association with adverse outcome in these patients.