Miller Fisher syndrome (MFS) is seen in about 1-5% of all cases of Gullain Barre syndrome. MFS is characterized by a classic triad of Ophthalmoplegia, Ataxia and Areflexia. Additional symptoms include bulbar palsy, motor weakness and sensory loss. However, ophthalmoplegia is the most important and consistent finding in this syndrome. The incidence in males and females is 2:1 and the mean age of presentation is around 43 years. The anti-GQ1b IgG antibody is found in about 90% of MFS cases and it is a very specific and a sensitive marker. We are presenting a case of Miller Fisher syndrome which manifested with ophthalmoplegia, hyporeflexia and ataxia with proptosis and chemosis in a 50 yrs old male.

Keywords: Gullain Barre Syndrome; Miller Fisher Syndrome; Ophthalmoplegia; Ataxia; Areflexia; Proptosis; Chemosis; GQ1b Antibody; IV Immunoglobulin.