Ingestion of yellow oleander as a mode of suicide is common in India and Southeast Asia. It is associated with severe cardiac toxicity. A combination therapy is suggested in a resource limited setting as Digoxin specific antibody fragments are not easily available for treatment of serious cardiac glycoside poisoning. Severe atrio-ventricular block can be treated with atropine or temporary cardiac pacing. Ventricular tachycardia can be treated with low dose cardioversionand ventricular fibrillation with low dose defibrillation depending on the presentation.

Keywords: Yellow Oleander Poisoning; Digoxin specific antibody fragments; Defibrillation; Cardioversion.