Cheiloscopy is derived from Greek word “Cheilos” which means lips. It is the study of characteristic pattern of elevations and depressions on labial mucosa. It is unique for every individual like finger prints and hence can be used to determine the sex and personal identity. Theory of uniqueness is a strong point used in the analysis of finger prints. Lip prints remain the same throughout life and are uninfluenced by injuries, diseases or environmental changes. This review discusses about various aspects of cheiloscopy.