AbstractHaemostasis, inflammation, proliferation, and remodelling are the steps that comprise the complex biological process of wound healing. Chronic wounds often remain static in the inflammatory stage of wound healing beyond the expected duration and resist healing. Biosilk or biomodified silk dressing is believed to aid in accelerating the wound healing process. The combination bio functionalised silk matrix with silver oxide and Centella asiatica, a medicinal plant with wound healing properties, has been found to be effective in managing chronic non-healing wounds.