Pemphigus vulgaris (PV) is a chronic autoimmune blistering disorders characterized by painful blister formation of the skin and mucous membranes. Although the prevalence of pemphigus vulgaris in children is unknown [1,2]. Toxic epidermal necrolysis (TEN) is a potentially life-threatening skin disorder characterized by widespread erythema, necrosis, and bullous detachment of the epidermis and mucous membranes, leads to sepsis and/or death [3]. It’s a report of a case with Pemphigus vulgaris with Toxic Epidermal Necrolysis. This study describes about a 12-year old male child presented with widespread erosions all over the body to the department of dermatology. At presentation child had multiple erosions over face, neck, trunk, axilla, lower limb, involving almost 30% of the body surface area with oral and genitalia mucosa ulceration. General and systemic examination was performed. All routine blood investigations were done. Then child was underwent pus culture/sensitivity test, based on the findings the child was treated with antibiotics and oral steroids.

Keywords: Pemphigus vulgaris; Toxic epidermal necrolysis; Blistering; Autoimmune.