Heparin administered subcutaneously, may cause adverse effects like pain, local irritation, erythema, hematoma and bruising at the site of injection. The researcher aimed to assess the effectiveness of the icepack application before and after administration of subcutaneous heparin injection on pain and bruise. Quantitative True experimental posttest only control group design was adopted and Systematic Random Sampling Technique With Kth sample was employed and 59 subjects were seggregated in to experimental and control groups by Flip a Coin method. The report of this study was found that there was a significant reduction of pain and bruise complications associated with subcutaneous heparin in critical care patients in Experimental and Control group with icepack application. Icepack application (cryotherapy) is a safe, non-invasive, pain-free, easy to self-administer therapy it can enhance patients sense of Control over there management side effects, it is cost effective and improves quality of life Keywords: Icepack, Pain and Bruising, Subcutaneous, Heparin, Critical Care Patients.