Abstract Background: Blood is life. Blood transfusion service (BTS) is an integral and indispensable part of the healthcare system. The priority objective of BTS is to ensure safety, adequacy, accessibility and efficiency of blood supply at all levels. Inspite of this large number of well-known complications are associated with blood transfusion like transfusion-transmissible infections, such as HIV, hepatitis B, hepatitis C and VDRL.
Aims & Objective: To study seroprevalence of HIV, HBV, HCV and syphilis in blood donors at tertiary care hospital.
Material & Methods: This was a retrospective study, where the data was procured from blood bank of the tertiary care hospital, Udaipur. All the blood donors in the records over a period of three years were included in the analysis. A through search of records revealed that total 3893 donors had been screened over period of 3 years. All the samples were screened for prevalence of HIV, HBsAg, HCV and syphilis. All the seropositive donors were further divided into voluntary and replacement donor categories.
Result: Of the total 3893 donors, 1405 were voluntary and 2488 were replacement donors. The seropositive rates amongst voluntary and replacement donors were 2.6% and 2.4% respectively. The overall prevalence of seropositivity for HIV, HBsAg, HCV and VDRL were 0.12%, 0.84%, 0.07% and 1.4% respectively.
Conclusion: On comparing the data of three years an increasing trend in seroprevalence of HBsAg, anti-HCV, VDRL and decreasing trend for HIV was observed.
Keywords: Transfusion-Transmissible Infectious Dieases; HIV; HBsAg; VDRL & HCV.