Background: Deaths due to road traffic accidents are one of the common forms of unnatural death and its history is as old as the invention of the wheel. Two wheeler riders are more vulnerable to sustain injuries as the external shell of the vehicle is absent to protect them as compared to light motor and heavy motor vehicles. Lost balance during two wheeler accidents further increases the risk of injury. Study Design: It’s a cross sectional Prospective study. Place of Study: At Mortuary of Department of Forensic Medicine, Gandhi Medical College Secunderabad. aterial and Method: The present study was done in mortuary of Department of Forensic Medicine, Gandhi Medical College Secunderabad. The collected data was entered in Microsoft Excel. Coding of the variables was done. SPSS version 11.5 was used for analysis. bservation and Discussion: Deaths due to accidents which were subjected to post mortem examination at Gandhi Medical College, Secunderabad are 1710 over a period of year. Among them deaths due to two wheeler accidents were 576 (33.68%). Males deaths are more and they accounted to 515 (89.41%) and females 61 (10.59%). 287 males (49.83%) and 4 females (0.69%) were riding the vehicle, male to female ratio is 8.44: 1. Deaths in the age group of 21 to 30 years  tolled as many as 164 lives (28.47%). Late night accidents (i.e. from 9 pm to 3 am) are commonly seen in the present study, 129 persons (22.40%) died on the spot, and another 124 person (21.53%) could survive up to more than 6 hours, but died within 24 hours of the accident. Maximum number of two wheeler accidents during late evening is because the traffic density ishigh during this time and is coupled with the poor infrastructure and  fall in traffic discipline. onclusion: A total of 576 victims of two­wheeler road traffic accident in this part ofworld were studied. The study highlights the need of compulsory implementation of helmet  wearing for motorcyclist and necessitates the need for taking urgent steps for establishing ambulance services and provision of pre­hospital care & trauma services to reduce mortality and morbidity. 

Keywords: Road Traffic Accidents; Motorcyclist; Autopsy; Injury.