Like fingerprints, lip prints are completely one-of-a-kind. Lip wrinkles come in a wide variety of shapes and sizes, but this review will focus on the differences between the sexes. There are forensic and non-forensic uses for lip prints. Chelioscopy is a powerful method for solving crimes by examining physical evidence left at the site. Greek chelioswich, meaning “lip’’ is where the term “cheiloscopy’’ originates. Both destructive and nondestructive techniques are used to categorize samples. There are numerous classifications that may be applied to lip prints due to their distinctive wrinkling and shape patterns; for instance, the clauco martin santos, Suzuki, and tsuchihashi classifications. Reviewing a large population, we find that both sexes share a preponderance of type IV groove patterns, that male and female lip prints exhibit no discernible variation over time, and that lip prints from the third gender display strikingly different characteristics.