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Indian Journal of Forensic Medicine and Pathology

Volume  16, Issue 2, April-June 2023, Pages 115-121
 

Original Article

Prenatal Autopsy Research on Diverse Congenital Anomalies: A Teaching Institutional Experience

Kusuma K N1 , Sumaya2 , Abhishek MG3

1Associate Professor, 2Assistant Professor, 3Professor and HOD, Department of Pathology, Adichunchanagiri Institute of Medical Sciences, BG Nagara 571448, Karnataka, India.

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DOI: https://dx.doi.org/10.21088/ijfmp.0974.3383.16223.4

Abstract

CONTEXT: According to estimates, 3-7% of the world’s population suff ers from congenital diseases, however the true percentage may differ substantially because cases in developing countries are sometimes not reported. Fetal autopsies are crucial for confi rming fetal congenital anomalies despite antenatal diagnostic techniques. In order to categorize congenital defects systemically and correlate these lesions with radiological results, the current investigation is being conducted.

AIMS: The present study is undertaken to study and categorizing the various congenital anomalies according system wise involvement and to correlate these lesions with radiological findings wherever available.

SETTINGS AND DESIGN: Cross sectional study.

METHODS AND MATERIAL: The retrospective study was carried out at the Pathology department. The request form was used to collect clinical and radiological information, and each case was reviewed in accordance with protocol.

STATISTICAL ANALYSIS USED: SPSS software was used for the statistical analysis. Descriptive statistics like frequency, mean and median were calculated. Finally, anomalies were categorized system wise.

RESULT:  The study comprised 85 cases with a 1.9:1 male to female fetal ratio. The most frequently affected system was a central nervous system. An unusual case of Patau and Down syndrome was identifed.

CONCLUSION: Fetal autopsy aids in the detection of a number of congenital malformations as well as the provision of information regarding the likelihood of these anomalies recurring in the future. Regular antenatal check-ups with specific diagnostic test help to avoid congenital anomalies in subsequent pregnancies.


Keywords : Congenital anomalies; Fetal autopsy; Cystic hygroma; Meningocele.
Corresponding Author : Sumaya