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Indian Journal of Forensic Medicine and Pathology

Volume  14, Issue 2 (Special Issue), April-June 2021, Pages 270-278
 

Review Article

Heavy Metal Toxicity: Impact on Human Health: A Review

Deepak K Sharma1, Risha J Nathan2, Rajeev Kumar3, A K Jain

1 Research Scholar 2 Assistant Professor 3 Associate Professor 4 Dean & Professor School of Basic and Applied Sciences, Galgotias University, Greater Noida 201310, Uttar Pradesh, India.

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DOI: http://dx.doi.org/10.21088/ijfmp.0974.3383.14221.37

Abstract

The detrimental effects of heavy metals on human health are known as several health risks are associated with heavy metal toxicity. Rapid industrialization and
enhanced use of metals in various industries resulted in the increased distribution of
heavy metals in the environment. Industrial wastes in the form of liquid and gaseous
efuents, as well as scrap in landflls are a major source of heavy metal pollution causing contamination of water bodies and the environment in general. Tese toxicants accumulate in the human body as individuals are exposed to them. Te toxicity of heavy
metals depends on various factors which include but not limited to amount of metal
(dose), exposure duration, age, gender and health status of individuals. Heavy metals
such as mercury, cadmium, arsenic, chromium, lead etc especially are of great concern
for public health due to their acute toxicity. Tese metals are potent enough to induce
multiple organ failure even at small concentrations. Studies have shown an association
between heavy metals and carcinogenicity. In the present work, a comprehensive analysis of toxicity of eleven heavy metal namely, aluminium, antimony, arsenic, bismuth,
cadmium, cobalt, iron, lead, mercury, tin and thallium has been reviewed along with
their analytical aspects and management. Clinical features of metal toxicity with diagnosis techniques and treatment including hospitalization and post-hospitalization
management are also elaborated.
 


Corresponding Author : Deepak Kumar Sharma