Infant mortality is considered as an important indicator of the health status of a community. Any reduction in infant mortality in developed countries will depend upon preventing one of its principal causes that is congenital anomalies. The decline in Infant mortality has been attributed to improved perinatal care, and better control of communicable diseases through proper vaccination. Maternal infections such as TORCH also contribute to the development of congenital malformations. It also highlights the health care importance in the preconceptional period. By giving more attention to this, now Rubella vaccine is included in the immunization schedule for adolescent girls as they are the prospective mothers. Infant death audit reveals that 50% of infant deaths are due to congenital anomalies and other brain related injuries. Most of the congenital anomalies are due to genetic causes except some develops due to vaccine preventable diseases like rubella. In order to overcome this problem, some preventive measures have to be taken like vaccination. 

Keywords: Rubella; German measles; Adolescent; Congenital anomalies.