Pranava yoga is one of the most popular pranayama yogic exercises. The present study was done to find out direct effect of Pranava yoga on cardiac output and peripheral resistance by using Impedance Cardiovasograph (Nivomon, L&T Medical’s). One hundred asymptomatic healthy male subjects, aged 17-23 years, participated voluntarily in the present study. Cardiac output, systemic peripheral resistance and other cardiovascular parameters were measured before and after Pranava yoga of 15 minutes. Statistically significant decrement was observed in all cardiovascular parameters after Pranava yoga but decrement was more pronounced in systolic blood pressure (SBP), heart rate (HR) , cardiac output (CO), stroke volume (SV), cardiac index (CI), stroke volume Index (SI) in comparison to decrement in diastolic blood pressure (DBP),  Systemic Peripheral Resistance (SPR) and Systemic Vascular Resistance Index (SVRI).