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DOI: http://dx.doi.org/10.21088/jcms.2454.7123.4118.9

Abstract

Aims: Effect of Intra luminal Papaverine injection on LIMA flow. Methods and Material: All the patients posted for CABG between January and July 2017, were included in this study. A total of 32 patients (26 male and 6 female ) met the inclusion criteria and were subjected to this study. LIMA pedicle was disconnected distally and blood flow was timed for a minute, collected into a vessel and measured. A soft bulldog clamp was placed proximally and 10 ml of 0.6% Papaverine was injected intra-luminally and a second bulldog clamp was placed distally. After an indwelling time of 1 min, both the bulldog clamps were removed and flow measured for the next 60 seconds. Both flows were measured maintaining similar mean arterial pressures. Results: Mean blood flow before Papaverine injection was 27.18 ml.Mean blood flow after Papaverine injection was 60.81 ml. Mean difference in blood flow was 33.93 ml. Conclusions: Intraluminal injection of Papaverine to LIMA after dissection treats spasm effectively. Papaverine injection injection improves LIMA flow significantly and the difference in flow was found to be statistically significant

 

 

Keywords : LIMA; PAPAVERINE; CABG. 

Corresponding Author : Ravikumar Nagashetty Kalyane, Associate Professor, Department of CVTS, Sri Jayadeva Institute of Cardiovascular sciences and research, Bengaluru, Karnataka 560069, India.