We are facing the worst pandemic of this 21st century in form of corona virus disease or COVID 19. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), initially presented as respiratory system disorders, but later on COVID-19 has been revealed to adversely related the cardiovascular system resulting to myocardial injury and dysfunction of endothelium mainly via the angiotensin converting enzyme 2 (ACE-2) receptor.1 COVID-19 affects the cardiovascular system in manner of both the short term by acute injury and long term by the chronic consequences. Seasonally the new variant of COVID 19 are recognizing globally since December 2019.2 Recently new variant like Omicron variant found with multiple mutant spikes which may be highly toxic or virulent. We are going to review our focus, scanning and realizing to update acute and chronic cardiovascular complications of COVID 19. Emergence of new variants and time being delay until herd immunity will be alarming for managing consequences of acute viral infection, however many vaccines are available, and mostly population are vaccinated for protection from different variants for future survival.3 Approach of an integrated health system with COVID 19 behaviour, integrated yoga approach for better immunity and vaccines are hopeful weapons to fight COVID 19 era followed by gene therapy or stem cell therapy for good future to avoid long term cardio vascular complications.4,5