Venous ulcers are common chronic leg ulcers that do not heal despite optimum wound-care practises. Pain and chronic/recurrent nature of venousulcer, poor quality of life, and poor outcome have significant negative impact on health, psyche and social life. Hence there is a need for exploration of effective techniques for healing of venous ulcers. In this article we report the manner in which we have explored various methods for augmentation of healing of venous ulcer such as hemoglobin spray, insulin therapy, vitamin D granule therapy, prolotherapy, low level laser therapy for wound bed preparation, heterografting with collagen and biosilk, hydrojet debridement, sucralfate therapy, RONPWT and finally split thickness skin grafting.