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Journal of Pharmaceutical and Medicinal Chemistry

Volume  2, Issue 1,  January - June 2016, Pages 109-113
 

Review Article

Oxazolones: A Review of Its Synthesis

Sajal Chhabra*, M. Shaqiqu Zamman*, M. Mumtaz Alam*, Mymoona Akhter*

Drug Design and Medicinal Chemistry Lab, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India.

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DOI: DOI: http://dx.doi.org/10.21088/jpmc.2395.6615.2116.11

Abstract

 Oxazolones or oxazolidinone or azlactones are five membered heterocyclic lactams derived from oxazole, also known as (4H)-oxazol 5-ones. Oxazolones have been very widely explored as important synthons for the synthesis of several biologically active molecules. Oxazolones derivatives have been used as starting materials for the synthesis of modified á- amino acids, peptides, other heterocycles, and biosensors. This review preesnts the various methods of synthesis of oxazolone derivatives.

Keywords: Oxazolone; Hippuric Acid; Benzoylglycine.


Corresponding Author : Mymoona Akhter*