In the present study we selected a plant namely allophylus serratus belonging to the family (sapindaceae) commonly known as Triputa (in Sanskrit). It is a large shrub or small tree grows up to 10 meters in height. It contains beta-sitosterol, phenacetamide, two flavonoid glycosides like luteolin-7-o-[beta]-D-glucopyranoside and apigenin- 4’-o[beta]-D-glucoside, quercetin, pinitol, rutin etc. It is useful in bone fractures, dislocations, Inflammations, ulcers, wounds, dyspepsia, anorexia and diarrhoea. The fruits are sweet cooling and nourishing tonic. Roots of widely grown plant Allophylus serratus reported to possess a very high amount of polyphenols and gallic acid which are well known potent antioxidants. Evaluation of the hepatoprotective activity was done by estimating the biochemical marker like SGPT, SGOT, ALP, LDH, total bilirubin, total protein in serum. EEAS significantly reversed the above parameters to near normal levels and the activity of EEAS was comparable to that of standard silymarin. The present studies indicated that the EEAS possess potent hepatoprotective activity comparable to standard LIV 52. The possible hepatoprotective mechanism of roots of llophylus serratus may be via its antioxidant property. 

Keywords: EEAS; Hepatotoxins; CCl 4, Histopathology.