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Journal of Pharmaceutical and Medicinal Chemistry

Volume  6, Issue 2, July – December 2020, Pages 83-88
 

Review Article

A Review on Methods of Analysis of Eslicarbazepine Acetate

Asif Husain1, Ahmad Nawed2, Sahil Haque3, Abdul Qadir4, Aqsa Khan5, Md Khurshed Alam6

1Professor, 2-6UG Scholar, Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110 062, India

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DOI: 1Professor, 2-6UG Scholar, Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110 062, India

Abstract

Antiepileptic drugs are used to treat neurological disorders characterized by recurrent epileptic seizures. Eslicarbazepine acetate (ESA), a promising antiepileptic agent, acts by blocking the voltagegated sodium channels. It is a prodrug and converted to eslicarbazepine. ESA is available in the market under different trade names like Aptiom, Zebinix, and Exalief. This review sheds light on the properties and essential ESA analysis methods like IR, HPLC, LC-MS, HPTLC, and UPLC.

Keywords: Epilepsy; ESA, Assay; UV; HPLC; MS.


Corresponding Author : Asif Husain