Aflatoxin is the most studied mycotoxin, due to both its toxicity to animals and people and its high carcinogenic potential.  Out of aflatoxins group, AFB1 is the most toxic.  The main biological effects on farm animals, including malabsorption of various nutrients, coagulopathy, decreased tissue integrity, poor growth, poor efficiency of feed conversion, enhanced susceptibility to infection, vaccine failures, drug failures, reproductive problems in males and females and Increased sensitivity to temperature extremes. Toxic residues of aflatoxin in animal products present a hazard to public health. A variety of physical, chemical and biological approaches to counteract the aflatoxin problem have been reported in the literature on mycotoxins; but large-scale, practical and cost-effective methods for detoxifying aflatoxin-containing feedstuffs are currently not available.