Abstract A trial was conducted to evaluate the effect of Lactobacillus and Saccharomyces Boulardii on performance of broilers. A total of 300 day old broilers were randomized in 5 groups, each with 6 replicates with (5x6) 10 birds per replicate. Basal diet (D1) (control) was prepared as per BIS specification. In that of Lactobacillus was added @ 100 and 200g/t in D2 and D3 ; Saccharomyces Boulardii(Sb) was added @ 500 and 1000g/t of feed respectively up to 42 days of age. The diets were iso nitrogenous and iso caloric. The results revealed, a significant (P<0.05) improvement in body weight gain, better FCR with increased concentrations of Lactobacillus (D3) and Saccharomyces Boulardii (D5) in feed. The results suggest that supplementation of Lactobacillus and Saccharomyces Boulardii @ 200g/t and 1000g/t of feed respectively improved the performance of the broilers by increasing the absorption capacity of the gut.