Cancer is a complex and challenging illness that not only affects the physical well-being of individuals but also takes a toll on their psychological and emotional health. Hospitalized cancer patients, in particular, face unique stressors associated with the illness, treatment protocols, and the uncertainty of their prognosis. Recognizing the importance of addressing the holistic needs of cancer patients, therapeutic counseling has emerged as a valuable intervention in the healthcare setting. This literature review aims to explore existing research on the effects of therapeutic counseling on the well-being of hospitalized cancer patients. This article is a narrative review and the included article was retrieved from electronic data hubs: NCBI liberty only; Google scholar; ResearchGate and PubMed, published in previous 10 years in the English language only and synthesized by thematic analysis mathod. literature supporting the positive effects of therapeutic counseling on the psychological well-being and overall quality of life of hospitalized cancer patients. However, further research is needed to explore the optimal timing, frequency, and specific modalities of counseling interventions to maximize their benefits. Understanding the nuances of therapeutic counseling in the context of cancer care is crucial for healthcare professionals to provide comprehensive support for patients facing the complex challenges of cancer and hospitalization.