Histopathology is the study of biologic tissues using a microscope to appreciate the diseased cells. It includes many processes from fixation till staining of the tissues using various chemical products. Though natural products are cost effective and nonhazardous, the efficiency and commercial availability of chemical products makes them indispensable. Exposure to the chemicals used in these processes cause various health hazards to the laboratory technicians, pathologists, and scientists working in the laboratory. Hence, there is a dire need to introduce healthy and biofriendly alternatives in the field. This literature review stress about the natural products and their efficiency to be used as alternatives for chemicals in the histopathology lab.

Keywords: Curcuma Longa EcoFriendly Stains; Histopathology; Hibiscus Rosasinensis; Lawsonia Inermis; Natural Alternatives; Pterocarpus Osun; Zingiber Officinale.