Background: The present study was designed to check the vasoconstrictive effects of bronchodilator and adrenergic in bettering cardiovascular disease in elective cesarean receiving crystalloid coloading throughout intrathecal bupivacaine injection. Material and Methods: 30 patients were selected in present study. Once pre-anesthetic analysis and investigations, the patients were explained regarding the procedure. Cluster E were received blood vessel (IV) bronchodilator five mg and cluster P were received blood vessel (IV) adrenergic a hundred weight unit once there'll be fall in maternal pulse force per unit area (SBP) > 20% from the bottom line. Results: The two teams, i.e., cluster one and cluster a pair of matched with relation to their age, weight and height. Overall, 7/15 (46.66%) patients within the adrenergic cluster and 7/15 (46.66%) patients within the bronchodilator cluster had one or additional episode of cardiovascular disease and needed one or additional bolus of vasoconstrictive. Compared with the baseline values, the amendment in mean rate among completely different intervals were found to be non-vital at any given time interval (p > 0.05). Conclusion: We conclude from the current study that bronchodilator five mg and adrenergic a hundred µg square measure equally economical in managing cardiovascular disease throughout spinal for cesarean.