Background and Aim: Point of care (POC) glucometry is most widely used method for monitoring blood sugar levels in the Intensive care unit (ICU). But, the accuracy of bedside glucometry using capillary blood is controversial in patients with shock. We aimed to compare the accuracy of POC glucometry with laboratory blood glucose measurements in patients with shock and requiring Noradrenaline infusion. Methods: This is Prospective, Observational study done on 100 consecutive patients admitted to ICU with shock categorized into two groups of 50 each, requiring two different doses of Noradrenaline infusion (Group A: 5 mcg/min and Group B: 10 mcg/min). POC capillary, POC venous and laboratory venous blood sugar measurements were simultaneously done in each patient. Results: ANOVA test was performed which showed that there was no statistical significance between the blood samples and also between the two groups (F value 0.022, p value 0.978). In Group A, stronger correlation was found between POC venous and lab venous blood sugar measurements (r=0.886, p<0.01) whereas in Group B, stronger correlation was found between POC capillary and lab venous blood sugar measurements (r=0.897, p<0.01) Conclusion: POC glucometer blood sugar estimation using capillary blood quite accurately correlates with the POC glucometry using venous blood and the laboratory values, even in patients with Noradrenaline infusion, provided all the confounding factors are eliminated before measuring blood sugar levels.