Background: In spite of tremendous advances in contemporary anesthesia practice, airway management continues to be of paramount importance to anesthesiologist. Hemodynamic changes are the major undesirable consequences of endotracheal intubation and laryngoscopy. The supraglottic airway device is a novel device that fills the gap in airway management between tracheal intubation and use of face mask. In view of this, the present study was undertaken to compare the performance of two supraglottic airway devices LMA supreme and LMA proseal. Methodology: Sixty ASA I-II patients scheduled for elective surgeries under general anaesthesia were randomised into two groups of 30 each. In Group S (n=30) LMA supreme and Group P (n=30) LMA proseal were used respectively. Both the devices were compared in relation to Ease of insertion assessed in terms of attempts taken and duration, Oropharyngeal leak pressure (OLP), Intracuff pressure(ICP), Ease of passing gastric tube and device related postoperative complications. Results: The insertion attempts were similar between two groups. Time taken to provide an effective airway was less in LMA supreme (Group S; 15.9 2.5 Group P; 17.8 1.6) p (0.001). OLP was significantly less in LMA supreme at 1, 15 and 30 min during anesthesia (Group S; 25.2 1.2, 22.8 1.3, 21.1±.9, Group P; 27.5±1.2,25.6±1.5,23.3±1.1) p (<0.05). ICP increased significantly in proseal LMA at 15 and 30 min during anesthesia (Group P; 68.3±1.3,76.8±2.6, Group S; 63.4±1.1, 68.3±1.32) p (<0.05). There was no significance difference in passing gastric tube and device related complications between both groups. Conclusion: Our finding suggested that LMA supreme was better in term of ease of insertion but LMA proseal had better OLP inspite of increase in ICP. Ease of passing gastric tube was similar in both. The complications of usage of LMA are minimal and similar in both the devices.