AbstractBack ground and Aim: “Pain” is the most feared symptom of disease or post-surgery especially in children because of its difficult to differentiate restlessness or crying due to pain, from that of hunger or fear in the children. There are different techniques available for pain relief in postoperative period like Non pharmacological approach, Parenteral narcotics, NSAIDS, Caudal blocks. We carried out the present study to compare the effect of rectal diclofenac and caudal bupivacaine for postoperative analgesia in pediatric patients for genitourinary and lower limb surgeries. Methodology: Fifty pediatric patients posted for elective genitourinary and lower limb surgeries of ASA grade I & II, aged 4 to 11 years of either sex were selected for this study. They were randomly divided in two groups of 25. Group A Received Caudal bupivacaine [0.25%] 1 ml/kg and Group B received Rectal Diclofenac suppository 2 mg/kg. postoperative pain was assessed by Hannallah score and analgesia given only when the score was > 7. Results: It was Observed that mean duration of time interval for first dose of analgesic was significantly longer in group B [8.56 hrs] than group A [4.2 hrs]. There were no significant hemodynamic changes, respiratory depression in both groups. Conclusion: This study concluded that Rectal diclofenac is a useful alternative to caudal bupivacaine and may offer advantages compared to caudal bupivacaine with regard to convenience of use for postoperative pain relief in children, as it is non- invasive method of pain relief.