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Indian Journal of Anesthesia and Analgesia

Volume  6, Issue 1, Jan-Feb 2019, Pages 135-143
 

Original Article

The Efficacy of Dexmedetomidine as Adjuvant in Caudal Block for Postoperative Pain Relief in Children

Sneha Sheelvanth1, Aparna Bagle2

1Senior Resident 2Professor, Dept of Anaesthesiology, Dr D.Y. Patil medical college, Hospital and Research Center, Dr. D.Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra 411018, India

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DOI: http://dx.doi.org/10.21088/ijaa.2349.8471.6119.19

Abstract

Introduction: In paediatric patients, optimum pain relief is a big challenge. An effective therapy to block or modify the physiological responses to painful stimuli is essential. Hence, here is an attempt to study the addition of dexmedetomidine, an alpha-2 adrenergic receptor agonist to bupivacaine with regard to analgesic potency and side effects. Material and Methods: After approval from the institution's ethics committee, the study was conducted to compare the effect of the addition of dexmedetomidine to bupivacaine in a caudal block for postoperative analgesia in paediatric infra-umbilical surgeries. Written informed parental or guardian consent was obtained.30 cases in the age group of 1 to 6 years were studied. They were randomly divided into two groups, Group N and Group D. • Group N (n=30) – 0.25% Bupivacaine 1 ml/kg+ 0.5 ml normal saline • Group D (n=30) – 0.25% Bupivacaine 1 ml/kg+Dexmedetomidine 1 μg/kg, making the volume to 0.5 ml. The total volume for the caudal block was 1 ml/kg in both groups. • after giving general anaesthesia child was placed in the left lateral position and a caudal block was performed under sterile conditions. The postoperative pain relief was evaluated using FLACC score hourly for the first 6 hours, 2 hourly up to 12 hours and then 4 hourly up to 24 hours. Sedation is evaluated by Ramsay's sedation score. Results and Conclusion: The addition of dexmedetomidine in the dose of 1µg/kg to 0.25% bupivacaine for caudal blockade showed that the duration of analgesia for Group N was 5.86±1.21 hrs and Group D was 15.5±3.02 hrs, without any significant haemodynamic changes, safe for use in paediatric patients without any adverse effects.


Keywords : Caudal Block; Bupivacaine; Dexmedetomidine. 
Corresponding Author : Aparna Abhijit Bagle