AbstractBackground: In laparoscopic surgery acute postoperative shoulder tip pain is a common entity despite the use of new drugs and novel drug delivery modalities, studies have shown that acute post-operative pain continues to be undermanaged. We tried to evaluate the efficacy of oral gabapentin for the relief of postoperative pain after laparoscopic surgery. Objective: To evaluate the effect of oral Gabapentin on postoperative shoulder pain after abdominal laparoscopy. Method: a prospective, randomized, clinically controlled study was conducted on 60 ASA grade I & grade II patients of either sex, aged between 18 to 65 years, planned for laparoscopic abdominal surgery under general anesthesia. Group G: 30 patients would receive 600 mg oral gabapentin 1 hour prior to surgery. Group M: 30 patients would receive tab multivitamin 1 hour prior to surgery. After that presence of post-operative shoulder pain and its severity was assessed by a Visual Analog Scale (VAS) at the beginning of surgery and 0, 2, 4, 8, 12,18,24 hours after the surgery. Results: The VAS score was lower in Group G when compared to Group M throughout the different time intervals during the first 24 hours. The incidence of post-operative laparoscopic shoulder pain in group M was 21 compared to group G where it was 12 in the first 24 hours postoperatively.