AbstractContext: Laryngeal mask airway (LMA) has revolutionized airway management in the administration of general anesthesia. Proseal LMA offers advantages like better sealing pressure, drain tube and lesser risk of aspiration. The present study is designed to compare the efficacy of Classic LMA (CLMA) and Proseal LMA (PLMA) in anesthetized patients coming for Gynaecological surgery. Methods and Material: 60 female patients of age group 18 years and older of American society of anaesthesiologists (ASA) physical status 1 and 2 who underwent elective gynaecological surgeries under general anaesthesia were divided into 2 groups, Group P (n = 30) comprised of patients who were managed with Proseal LMA and Group C (n = 30) comprised of patients who were managed with classic LMA. Outcomes measured were Fibreoptic grading of LMA placement, Oropharyngeal sealing pressure (OSP), Ease of insertion, Time taken for insertion, Number of attempts and incidence of Complications. Results: The oropharyngeal sealing pressure was found to be significantly higher with proseal LMA(31.27±5.0 cm H2O) than classic LMA (17±3.4 cm H2O). The best fiberoptic score (grade 4) were found in 22 patients of Proseal LMA group and 7 patients of Classic LMA group which was statistically significant. Conclusions: Proseal LMA is superior to Classic LMA in anatomical placement defined in terms of clinical end points, oropharyngeal sealing pressure and fiberoptic view in anesthetised patients coming for Gynaecological surgery.